Publications

2022

R. Risman, A. Abdelhamid, J.W. Weisel, B. Bannish, V. Tutwiler. Structural mechanisms governing external fibrinolysis of contracted blood clots. Biophys J. 2022;S0006-3495(22)00596-3.

R. Spiewak. A. Gosselin, D. Merinov, R.I. Litvinov, J.W. Weisel*, V. Tutwiler*, P.K. Purohit*. Biomechanical origins of inherent tension in fibrin networks. J Mech Behav Biomed Mater. 2022;133:105328

2021

V. Tutwiler, R.I. Litvinov, A. Protopopova, C. Nagaswami, C. Villa, E. Woods, O. Abdulmalik, D.L. Siegel, J.E. Russell, V.R. Muzykantov, W.A. Lam, D.R. Myers, J.W. Weisel. Pathologically stiff erythrocytes impede contraction of blood clots: reply to a comment. J Thromb Haemost. 2021; 19(11):2894-2895.

V. Tutwiler. To deform or not to deform: an evolutionary basis of mammalian red blood cell deformability. Biophys J. 2021; 120(17):35393540.

V. Tutwiler, F. Maksudov, R.I. Litvinov, J.W. Weisel, V. Barsegov. Strength and deformability of fibrin clots: biomechanics, thermodynamics, and mechanisms of rupture. Acta Biomater. 2021; S1742-7061(21):00428-1.

2020

V. Tutwiler, J. Singh, R.I. Litvinov, J.L. Bassani, P.K. Purohit, J.W. Weisel. Rupture Resistance of Blood Clots. Science Advances. 2020 6(35): eabc0496

K.A. Jansen, A. Zhurov, B.E. Vos, G. Portale, D. Hermida-Merino, R.I. Litvinov, V. Tutwiler, N.A. Kurniawan, W. Bras, J.W. Weisel, V. Barsegov, G.H. Koenderink. Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling. Soft Matter. 2020 16:8272-8283.

2019

V. Tutwiler, A.D. Peshkova, G. Le Mihn, S. Zaytsev, R.I. Litvinov, D.B. Cines, J.W. Weisel. Blood clot contraction differently modulated internal and external fibrinolysis. Journal of Thrombosis and Hemostasis. 2019 17(2):361-370

2018

V. Tutwiler, A.R. Mukhitov, A.D. Peshkova, G. Le Minh, R.R. Khismatullin, J. Vicksman, C. Nagaswami, R.I. Litvinov, J.W. Weisel Shape changes of erythrocytes during blood clot contraction and the structure of polyhedrocytes. Scientific Reports. 2018 8:1790

J. Dai, D.Madeeva, V. Hayes, H.S. Ahn, V. Tutwiler, G.M. Arepally, D.B. Cines, M. Poncz and L. Rauova. Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia. Blood. 2018 132(7):727-734.

P. Ma, S. Gupta, S. Sampietro, D. DeHanlian, V. Tutwiler, A. Tang, T.J. Stalker, L.F. Brass. The role of RGS10 in modulating the hemostatic response to injury. Blood Advances. 2018 2:2145-215.

A.D. Peshkova, D.V. Malyasysov, R.A. Bredikhin, G. Le Minh, I.A. Andrianova, V. Tutwiler, C. Nagaswami, J.W. Weisel, R.I. Litvinov. Reduced contraction of blood clots in venous thromboembolism is a potential thrombogenic and embologenic mechanism. TH Open. 2018 02(01)e104-e115

2017

V. Tutwiler, H. Wang, R.I. Litvinov, J.W. Weisel. V.B. Shenoy. Interplay of Platelet Contractility and Elasticity of Fibrin/Erythrocytes in Blood Clot Contraction. Biophys J. 2017 112(4):714-723

AD Peshkova, LM Giang, V Tutwiler, I.A. Andrianova, J.W. Weisel, R.I. Litvinov. A new link between inflammation and blood clotting: activated monocytes enhance clot contraction. Scientific Reports. 2017 7:5149

V. Tutwiler, A.D. Peshkova, I.A. Andrianova, D.R. Khasanova, J.W. Weisel, R.I. Litvinov. Contraction of blood clots is impaired in acute ischemic stroke. Athero Thromb Vasc Biol. 2017 37:271-279

2016

V. Tutwiler, R.I. Litvinov, A.P Lozhkin, A.D. Peshkova, T. Lebedeva, F.I. Ataullakhanov, K.L. Spiller, D.B. Cines, J.W. Weisel. Kinetics and mechanics of clot contraction are governed by the molecular and cellular composition of the blood. Blood. 2016 127(1):149-159.

V. Tutwiler, D. Madeeva, H. Ahn, I. Andrianova, V. Hayes, X.L. Zheng, C.B. Cines, S. McKenzie, M. Poncz, L. Rauova, L. Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia. Blood. 2016 127(4):464-472.